Biomedical Physics > People > Philip Bittihn

Philip Bittihn

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I am working at Max Planck Institute for Dynamics and Self-Organization in the Biomedical Physics Group headed by Prof. Dr. Stefan Luther. My research interests are centered around non-linear dynamics and biophysics. I am highly fascinated by complexity and emergent properties of complex systems, which I try to approach by employing the concepts of nonlinear dynamics. My area of expertise includes mathematical models of excitable media (esp. cardiac tissue), numerical simulations and data analysis. I am currently interested in the connection between heterogeneity in the system and its effect on the dynamics. The Ph.D. program I recently finished was the International Max Planck Research School for "Physics of Biological and Complex Systems".

Curriculum Vitae

since June 2013 PostDoc in the Biomedical Physics Group
May 2009
- June 2013
Ph.D. student in the Biomedical Physics Group
Supported by an excellence stipend awarded by the International Max Planck Research School for Physics of Biological and Complex Systems (May 2009 to April 2012) and a Max Planck stipend (May 2012 to June 2013)
Title of Thesis: Complex Structure and Dynamics of the Heart
Mar 2009 Berliner-Ungewitter Prize of the Berliner-Ungewitter Foundation for outstanding graduation (Diploma)
Mar 2009   Diploma at the Third Institute of Physics, graduation with honors, Georg-August University Göttingen
Title of Thesis: Control of Spiral Wave Activity in Excitable Media
Nov 2003
- Mar 2009
Studies of Physics at the Georg-August University Göttingen
Scholar of the German National Academic Foundation ("Studienstiftung des deutschen Volkes")

Member of the Society for Industrial and Applied Mathematics (SIAM), the (US) Biophysical Sosciety (BPS) and the Deutsche Physikalische Gesellschaft (DPG)

Publications

P. Bittihn, M. Hörning, S. Luther, Negative curvature boundaries as wave emitting sites for the control of biological excitable media. Physical Review Letters 109, 118106 (2012)

S. Luther, F.H. Fenton, B. G. Kornreich, A. Squires, P. Bittihn, D. Hornung, M. Zabel, J. Flanders, A. Gladuli, L. Campoy, E. M. Cherry, G. Luther, G. Hasenfuss, V. I. Krinsky, A. Pumir, R. F. Gilmour Jr, E. Bodenschatz, Low-energy control of electrical turbulence in the heart. Nature 475 (7355), 235 (2011)

S. Petitprez, A. F. Zmoos, J. Ogrodnik, E. Balse, N. Raad, S. El-Haou, M. Albesa, P. Bittihn, S. Luther, S. E. Lehnart, S. N. Hatem, A. Coulombe, H. Abriel, SAP97 and Dystrophin Macromolecular Complexes Determine Two Pools of Cardiac Sodium Channels Nav1.5 in Cardiomyocytes. Circulation research 110, 312 (2010)

A. Behrend, P. Bittihn, S. Luther, Understanding and predicting the response of pinned vortices to periodic electric far-field stimuli. Biomedizinische Technik 55 S1, 339 (2010)

A. Behrend, P. Bittihn, S. Luther, Predicting Unpinning Success Rates for a Pinned Spiral in an Excitable Medium. Computing in Cardiology 37, 345 (2010)

S. Berg, P. Bittihn, S. Luther, U. Parlitz, Fast parallel simulations of excitable media dynamics on multicore processors and graphics processing units. Proceedings of the 6th ESGCO 2010, April 12-14, 2010, Berlin, Germany

P. Bittihn, A. Squires, G. Luther, E. Bodenschatz, V. Krinsky, U. Parlitz, and S. Luther, Phase-resolved analysis of the susceptibility of pinned spiral waves to far-field pacing in a two-dimensional model of excitable media. Phil. Trans. R. Soc. A 368, 2221-2236 (2010)

P. Bittihn, G. Luther, E. Bodenschatz, V. Krinsky, U. Parlitz and S. Luther, Far field pacing supersedes anti-tachycardia pacing in a generic model of excitable media. New Journal of Physics 10, 103012 (2008)

J. Klein, A. Vilanova, P. Ledochowitsch, P. Bittihn, H. K. Hahn, O. Konrad, J. Rexilius, and H.-O. Peitgen, Improving perception of brain structure using fiber clustering. SPIE Newsroom, doi: 10.1117/2.1200707.0771 (2007)

J. Klein, P. Bittihn, P. Ledochowitsch, H. K. Hahn, O. Konrad, J. Rexilius and H.-O. Peitgen, Grid-based spectral fiber clustering. Proc. SPIE 6509, 65091E (2007)

Invited talks

P. Bittihn "The Role of Cardiac Structural Heterogeneity during Electric-Field Stimulation" High Definition Physiology Project Symposium 2013, Tokyo

P. Bittihn "The Role of Cardiac Structural Heterogeneity during Electric-Field Stimulation", Keio University, 2013

Talks

P. Bittihn "The Role of Cardiac Tissue Anatomy during Electric-Field Stimulation", SIAM Conference on Applications of Dynamical Systems 2013, Snowbird, Utah

P. Bittihn "Theory and application of low-energy pacing strategies for the control of cardiac dynamics", Annual Meeting of the German Biophysical Society 2012, Göttingen, Germany

P. Bittihn, M. Hörning, S. Luther “Cardiac tissue heterogeneity mediates electrical stimulation effects”, BioCircuits Institute, May 2012, UCSD, CA, USA

P. Bittihn, M. Hörning, S. Luther “Cardiac tissue heterogeneity mediates electrical stimulation effects”, 12th Experimental Chaos and Compmlexity Conference, 2012, Ann Arbor, MI, USA

P. Bittihn, M. Hörning, S. Luther “Dynamical impact of structural heterogeneities in electrically-stimulated cardiac tissue”, DPG Spring Meeting 2012, Berlin, Germany

P. Bittihn, D. Hornung, S. Richter, S. Luther “Dynamical response of cardiac tissue to electric-field stimulation”, Dynamics Days Europe 2011, Oldenburg, Germany

P. Bittihn, D. Hornung, S. Luther “Low-Energy Control of Cardiac Dynamics: Virtual Electrode Formation at Tissue Boundaries”, International Scientific Conference on Physics and Control 2011, León, Spain

P. Bittihn, U. Parlitz, S. Luther and F. Fenton “Lyapunov Stability Analysis of Generic Activation Patterns in Excitable Media”, SIAM Conference DSPDEs 2010, Barcelona

P. Bittihn “Control of Spiral Wave Activity in Excitable Media with Application to Cardiac Dynamics”, ICTS BioModVis Workshop Jacobs University 2010, Bremen

P. Bittihn, E. Bodenschatz, V. Krinsky, U. Parlitz and S. Luther “Control of Spiral Wave Activity in Heterogeneous Excitable Media”, Dynamics Days Europe 2009, Göttingen

P. Bittihn, U. Parlitz, E. Bodenschatz, V. Krinsky and S. Luther “Far field pacing supersedes anti-tachycardia pacing in a generic model of excitable media”, SIAM Conference on Applications of Dynamical Systems 2009, Snowbird, Utah

P. Bittihn, G. Luther, U. Parlitz, E. Bodenschatz, V. Krinsky and S. Luther “Two mechanisms for Control of Chaos in the Heart Induced by Pinned Rotating Waves”, 10th Experimental Chaos Conference 2008, Catania

P. Bittihn, U. Parlitz and S. Luther “Pattern Control in a Two-Dimensional Model of Cardiac Tissue”, Conference of the German Physical Society 2008, Dynamics and Statistical Physics Division, Berlin

 

Posters

P. Bittihn, M. Hörning, D. Hornung, F. H. Fenton, S. Luther "Electric-field based control strategies for cardiac tissue", Annual Meeting of the (US) Biophysical Society 2012, Philadelphia, PA, USA